SH2B1 promotes epithelial‐mesenchymal transition through the IRS1/β‐catenin signaling axis in lung adenocarcinoma

Lung adenocarcinoma (LADC), the most prevalent type of human lung cancer, is characterized by many molecular abnormalities. SH2B1, a member of the SH2‐domain containing family, have recently been shown to act as tumor activators in multiple cancers, including LADC. However, the mechanisms underlying...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Carcinog
Hauptverfasser: Wang, Shaoqiang, Cheng, Yuanda, Gao, Yang, He, Zhiwei, Zhou, Wolong, Chang, Ruimin, Peng, Zhenzi, Zheng, Yingying, Duan, Chaojun, Zhang, Chunfang
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900930/
https://ncbi.nlm.nih.gov/pubmed/29380446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22788
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