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Anticancer Effects of Gingerol in Retinoblastoma Cancer Cells (RB355 Cell Line) Are Mediated via Apoptosis Induction, Cell Cycle Arrest and Upregulation of PI3K/Akt Signaling Pathway

BACKGROUND: The main aim of the current investigation was to study the antiproliferative activity of gingerol in RB355 human retinoblastoma cancer cells. The effects of gingerol on apoptosis induction, cell cycle arrest, and PI3K/Akt signaling pathway were also evaluated. MATERIAL/METHODS: MTT cell...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Med Sci Monit
Main Authors: Meng, Bo, Ii, Hongyi, Qu, Wei, Yuan, Huiping
Format: Artigo
Jezik:Inglês
Izdano: International Scientific Literature, Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900802/
https://ncbi.nlm.nih.gov/pubmed/29615601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.905450
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