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Anticancer Effects of Gingerol in Retinoblastoma Cancer Cells (RB355 Cell Line) Are Mediated via Apoptosis Induction, Cell Cycle Arrest and Upregulation of PI3K/Akt Signaling Pathway

BACKGROUND: The main aim of the current investigation was to study the antiproliferative activity of gingerol in RB355 human retinoblastoma cancer cells. The effects of gingerol on apoptosis induction, cell cycle arrest, and PI3K/Akt signaling pathway were also evaluated. MATERIAL/METHODS: MTT cell...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Meng, Bo, Ii, Hongyi, Qu, Wei, Yuan, Huiping
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900802/
https://ncbi.nlm.nih.gov/pubmed/29615601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.905450
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