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Anticancer Effects of Gingerol in Retinoblastoma Cancer Cells (RB355 Cell Line) Are Mediated via Apoptosis Induction, Cell Cycle Arrest and Upregulation of PI3K/Akt Signaling Pathway

BACKGROUND: The main aim of the current investigation was to study the antiproliferative activity of gingerol in RB355 human retinoblastoma cancer cells. The effects of gingerol on apoptosis induction, cell cycle arrest, and PI3K/Akt signaling pathway were also evaluated. MATERIAL/METHODS: MTT cell...

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Pubblicato in:Med Sci Monit
Autori principali: Meng, Bo, Ii, Hongyi, Qu, Wei, Yuan, Huiping
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Scientific Literature, Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900802/
https://ncbi.nlm.nih.gov/pubmed/29615601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.905450
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