Homocysteine regulates fatty acid and lipid metabolism in yeast

S-Adenosyl-l-homocysteine hydrolase (AdoHcy hydrolase; Sah1 in yeast/AHCY in mammals) degrades AdoHcy, a by-product and strong product inhibitor of S-adenosyl-l-methionine (AdoMet)-dependent methylation reactions, to adenosine and homocysteine (Hcy). This reaction is reversible, so any elevation of...

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Vydáno v:J Biol Chem
Hlavní autoři: Visram, Myriam, Radulovic, Maja, Steiner, Sabine, Malanovic, Nermina, Eichmann, Thomas O., Wolinski, Heimo, Rechberger, Gerald N., Tehlivets, Oksana
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
Lipids
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900771/
https://ncbi.nlm.nih.gov/pubmed/29414770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809236
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