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A molecular perspective of mammalian autophagosome biogenesis

Autophagy is a highly conserved process and is essential for the maintenance of cellular homeostasis. Autophagy occurs at a basal level in all cells, but it can be up-regulated during stress, starvation, or infection. Misregulation of autophagy has been linked to various disorders, including cancer,...

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Pubblicato in:J Biol Chem
Autori principali: Mercer, Thomas J., Gubas, Andrea, Tooze, Sharon A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900756/
https://ncbi.nlm.nih.gov/pubmed/29371398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.810366
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