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Critical Role for G(i/o)-Protein Activity in the Dorsal Striatum in the Reduction of Voluntary Alcohol Intake in C57Bl/6 Mice

The transition from non-dependent alcohol use to alcohol dependence involves increased activity of the dorsal striatum. Interestingly, the dorsal striatum expresses a large number of inhibitory G-protein-coupled receptors (GPCRs), which when activated may inhibit alcohol-induced increased activity a...

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Bibliographic Details
Published in:Front Psychiatry
Main Authors: Robins, Meridith T., Chiang, Terrance, Mores, Kendall L., Alongkronrusmee, Doungkamol, van Rijn, Richard M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900748/
https://ncbi.nlm.nih.gov/pubmed/29686629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2018.00112
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