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The glycan‐dependent ERAD machinery degrades topologically diverse misfolded proteins
Many soluble and integral membrane proteins fold in the endoplasmic reticulum (ER) with the help of chaperones and folding factors. Despite these efforts, protein folding is intrinsically error prone and amino acid changes, alterations in post‐translational modifications or cellular stress can cause...
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| Udgivet i: | Plant J |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5900737/ https://ncbi.nlm.nih.gov/pubmed/29396984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tpj.13851 |
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