Llwytho...

The glycan‐dependent ERAD machinery degrades topologically diverse misfolded proteins

Many soluble and integral membrane proteins fold in the endoplasmic reticulum (ER) with the help of chaperones and folding factors. Despite these efforts, protein folding is intrinsically error prone and amino acid changes, alterations in post‐translational modifications or cellular stress can cause...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Plant J
Prif Awduron: Shin, Yun‐Ji, Vavra, Ulrike, Veit, Christiane, Strasser, Richard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900737/
https://ncbi.nlm.nih.gov/pubmed/29396984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tpj.13851
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!