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Characterization of the molecular crosstalk within the essential Grc3/Las1 pre-rRNA processing complex

Grc3 is an essential well-conserved eukaryotic polynucleotide kinase (PNK) that cooperates with the endoribonuclease Las1 to process the preribosomal RNA (rRNA). Aside from being dependent upon Las1 for coordinated kinase and nuclease function, little is known about Grc3 substrate specificity and th...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Pillon, Monica C., Sobhany, Mack, Stanley, Robin E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900568/
https://ncbi.nlm.nih.gov/pubmed/29440475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.065037.117
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