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IGF-Binding Proteins: Why Do They Exist and Why Are There So Many?

Insulin-like growth factors (IGFs) are key growth-promoting peptides that act as both endocrine hormones and autocrine/paracrine growth factors. In the bloodstream and in local tissues, most IGF molecules are bound by one of the members of the IGF-binding protein (IGFBP) family, of which six distinc...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Allard, John B., Duan, Cunming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900387/
https://ncbi.nlm.nih.gov/pubmed/29686648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00117
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