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Cigarette smoke dampens antiviral signaling in small airway epithelial cells by disrupting TLR3 cleavage

Cigarette smokers and people exposed to second-hand smoke are at an increased risk for pulmonary viral infections, and yet the mechanism responsible for this heightened susceptibility is not understood. To understand the effect of cigarette smoke on susceptibility to viral infection, we used an air-...

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Bibliografski detalji
Izdano u:Am J Physiol Lung Cell Mol Physiol
Glavni autori: Duffney, Parker F., McCarthy, Claire E., Nogales, Aitor, Thatcher, Thomas H., Martinez-Sobrido, Luis, Phipps, Richard P., Sime, Patricia J.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900359/
https://ncbi.nlm.nih.gov/pubmed/29351447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00406.2017
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