Cigarette smoke dampens antiviral signaling in small airway epithelial cells by disrupting TLR3 cleavage

Cigarette smokers and people exposed to second-hand smoke are at an increased risk for pulmonary viral infections, and yet the mechanism responsible for this heightened susceptibility is not understood. To understand the effect of cigarette smoke on susceptibility to viral infection, we used an air-...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Duffney, Parker F., McCarthy, Claire E., Nogales, Aitor, Thatcher, Thomas H., Martinez-Sobrido, Luis, Phipps, Richard P., Sime, Patricia J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900359/
https://ncbi.nlm.nih.gov/pubmed/29351447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00406.2017
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