Ca(2+) signalling in mouse urethral smooth muscle in situ: role of Ca(2+) stores and Ca(2+) influx mechanisms

KEY POINTS: Contraction of urethral smooth muscle cells (USMCs) contributes to urinary continence. Ca(2+) signalling in USMCs was investigated in intact urethral muscles using a genetically encoded Ca(2+) sensor, GCaMP3, expressed selectively in USMCs. USMCs were spontaneously active in situ, firing...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Drumm, Bernard T., Rembetski, Benjamin E., Cobine, Caroline A., Baker, Salah A., Sergeant, Gerard P., Hollywood, Mark A., Thornbury, Keith D., Sanders, Kenton M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Muscle
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899989/
https://ncbi.nlm.nih.gov/pubmed/29383731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275719
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