Phosphodiesterase‐5 inhibition potentiates cerebrovascular reactivity in chronic traumatic brain injury

BACKGROUND: Traumatic cerebrovascular injury (TCVI), a common consequence of traumatic brain injury (TBI), presents an attractive therapeutic target. Because phosphodiesterase‐5 (PDE5) inhibitors potentiate the action of nitric oxide (NO) produced by endothelial cells, they are candidate therapies f...

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Detalles Bibliográficos
Publicado en:Ann Clin Transl Neurol
Main Authors: Kenney, Kimbra, Amyot, Franck, Moore, Carol, Haber, Margalit, Turtzo, L. Christine, Shenouda, Christian, Silverman, Erika, Gong, Yunhua, Qu, Bao‐ Xi, Harburg, Leah, Wassermann, Eric M., Lu, Hanzhang, Diaz‐Arrastia, Ramon
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899908/
https://ncbi.nlm.nih.gov/pubmed/29687019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.541
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