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Hypothesis: structural heterogeneity of the unfolded proteins originating from the coupling of the local clusters and the long-range distance distribution

We propose a hypothesis that explains two apparently contradicting observations for the heterogeneity of the unfolded proteins. First, the line confocal method of the single-molecule Förster resonance energy transfer (sm-FRET) spectroscopy revealed that the unfolded proteins possess broad peaks in t...

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Detalhes bibliográficos
Publicado no:Biophys Rev
Main Authors: Takahashi, Satoshi, Yoshida, Aya, Oikawa, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899747/
https://ncbi.nlm.nih.gov/pubmed/29446056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-018-0405-8
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