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Age-dependent cellular and behavioral deficits induced by molecularly targeted drugs are reversible
Newly developed targeted anti-cancer drugs inhibit signaling pathways commonly altered in adult and pediatric cancers. However, as these pathways are also essential for normal brain development, concerns have emerged of neurological sequelae resulting specifically from their application in pediatric...
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| Publicado no: | Cancer Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5899652/ https://ncbi.nlm.nih.gov/pubmed/29559476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-2254 |
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