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Analysis of Drug Development Paradigms for Immune Checkpoint inhibitors

Immune checkpoint inhibitors have unique toxicities and response kinetics compared to cytotoxics and gene-targeted anti-cancer agents. We investigated the impact of innovative/accelerated immunotherapy drug development/approval models on the accuracy of safety and efficacy assessments by searching t...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Jardim, Denis L., de Melo Gagliato, Débora, Giles, Francis J., Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899646/
https://ncbi.nlm.nih.gov/pubmed/29212781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1970
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