OSR1 regulates a subset of inward rectifier potassium channels via a binding motif variant

The with-no-lysine (K) (WNK) signaling pathway to STE20/SPS1-related proline- and alanine-rich kinase (SPAK) and oxidative stress-responsive 1 (OSR1) kinase is an important mediator of cell volume and ion transport. SPAK and OSR1 associate with upstream kinases WNK 1–4, substrates, and other protein...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Taylor, Clinton A., An, Sung-Wan, Kankanamalage, Sachith Gallolu, Stippec, Steve, Earnest, Svetlana, Trivedi, Ashesh T., Yang, Jonathan Zijiang, Mirzaei, Hamid, Huang, Chou-Long, Cobb, Melanie H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899495/
https://ncbi.nlm.nih.gov/pubmed/29581290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802339115
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