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Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas
Type 1 diabetes is characterized by autoimmune destruction of β cells located in pancreatic islets. However, tractable in vivo models of human pancreatic β cells have been limited. Here, we generated xenogeneic human pancreatic β-like cells in the mouse pancreas by orthotopic transplantation of stem...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5899428/ https://ncbi.nlm.nih.gov/pubmed/29599125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702059115 |
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