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Non-endometrioid and high-grade endometrioid endometrial cancers show DNA fragmentation factor 40 (DFF40) and B-cell lymphoma 2 protein (BCL2) underexpression, which predicts disease-free and overall survival, but not DNA fragmentation factor 45 (DFF45) underexpression

BACKGROUND: The expression of DNA fragmentation factor 45 (DFF45) and B-cell lymphoma 2 (BCL2) in glands of the normal human endometrium is related to phases of the menstrual cycle and decreases after menopause, whereas the expression of DNA fragmentation factor 40 (DFF40) is stable. Moreover, DF45,...

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Publicat a:BMC Cancer
Autors principals: Banas, Tomasz, Pitynski, Kazimierz, Okon, Krzysztof, Winiarska, Aleksandra
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899339/
https://ncbi.nlm.nih.gov/pubmed/29653556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4333-6
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