Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development

BACKGROUND: The interplay of epigenetic processes and the intestinal microbiota may play an important role in intestinal development and homeostasis. Previous studies have established that the microbiota regulates a large proportion of the intestinal epithelial transcriptome in the adult host, but m...

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Vydáno v:Genome Med
Hlavní autoři: Pan, Wei-Hung, Sommer, Felix, Falk-Paulsen, Maren, Ulas, Thomas, Best, Lena, Fazio, Antonella, Kachroo, Priyadarshini, Luzius, Anne, Jentzsch, Marlene, Rehman, Ateequr, Müller, Fabian, Lengauer, Thomas, Walter, Jörn, Künzel, Sven, Baines, John F., Schreiber, Stefan, Franke, Andre, Schultze, Joachim L., Bäckhed, Fredrik, Rosenstiel, Philip
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899322/
https://ncbi.nlm.nih.gov/pubmed/29653584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0534-5
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