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Abnormal visual gain control and excitotoxicity in early-onset Parkinson’s disease Drosophila models

The excitotoxic theory of Parkinson’s disease (PD) hypothesizes that a pathophysiological degeneration of dopaminergic neurons stems from neural hyperactivity at early stages of disease, leading to mitochondrial stress and cell death. Recent research has harnessed the visual system of Drosophila PD...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Himmelberg, Marc M., West, Ryan J. H., Elliott, Christopher J. H., Wade, Alex R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899316/
https://ncbi.nlm.nih.gov/pubmed/29142100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00681.2017
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