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Topical Glycyrrhizin Is Therapeutic for Pseudomonas aeruginosa Keratitis

Purpose: Glycyrrhizin (GLY), an inhibitor of high-mobility group box 1 (HMGB1) protects prophylactically against Pseudomonas aeruginosa keratitis. However, the therapeutic potential of GLY to enhance an antibiotic has not been tested and is our purpose. Methods: C57BL/6 mice (B6) were infected with...

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Detalles Bibliográficos
Publicado en:J Ocul Pharmacol Ther
Main Authors: Ekanayaka, Sandamali A., McClellan, Sharon A., Barrett, Ronald P., Hazlett, Linda D.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899296/
https://ncbi.nlm.nih.gov/pubmed/29236588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2017.0094
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