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Acute lysyl oxidase inhibition alters microvascular function in normotensive but not hypertensive men and women

The lysyl oxidase (LOX) family of enzymes regulates collagen cross-linking. LOX is upregulated in hypertension, increasing vascular stiffness. In vivo human research is sparse, as long-term LOX inhibition in animals causes vascular instability. Our aim was to evaluate the effects of LOX inhibition o...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Craighead, Daniel H., Wang, Huilei, Santhanam, Lakshmi, Alexander, Lacy M.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899263/
https://ncbi.nlm.nih.gov/pubmed/29167120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00521.2017
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