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Cell-free prediction of protein expression costs for growing cells

Translating heterologous proteins places significant burden on host cells, consuming expression resources leading to slower cell growth and productivity. Yet predicting the cost of protein production for any given gene is a major challenge, as multiple processes and factors combine to determine tran...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Borkowski, Olivier, Bricio, Carlos, Murgiano, Michela, Rothschild-Mancinelli, Brooke, Stan, Guy-Bart, Ellis, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899134/
https://ncbi.nlm.nih.gov/pubmed/29654285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03970-x
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