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Capsaicin upregulates HDAC2 via TRPV1 and impairs neuronal maturation in mice
Transient receptor potential vanilloid 1 (TRPV1) affects mood and neuroplasticity in the brain, where its role is poorly understood. In the present study we investigated whether capsaicin (8-methyl-N-vanillyl-trans-6-nonenamide), an agonist of TRPV1, induced chromatin remodeling and thereby altered...
Gespeichert in:
| Veröffentlicht in: | Exp Mol Med |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5898893/ https://ncbi.nlm.nih.gov/pubmed/29520110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.289 |
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