Intestinal manipulation affects mucosal antimicrobial defense in a mouse model of postoperative ileus

AIM: To explore the effects of abdominal surgery and interleukin-1 signaling on antimicrobial defense in a model of postoperative ileus. METHODS: C57BL/6 and Interleukin-1 receptor type I (IL-1R1) deficient mice underwent intestinal manipulation to induce POI. Expression of mucosal IL-1α, IL-1β and...

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Publicado en:PLoS One
Main Authors: Stein, Kathy, Hieggelke, Lena, Schneiker, Bianca, Lysson, Mariola, Stoffels, Burkhard, Nuding, Sabine, Wehkamp, Jan, Kikhney, Judith, Moter, Annette, Kalff, Joerg C., Wehner, Sven
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898729/
https://ncbi.nlm.nih.gov/pubmed/29652914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195516
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