The Effect of Tissue Preparation and Donor Age on Striatal Graft Morphology in the Mouse

Huntington's disease (HD) is a progressive neurodegenerative disease in which striatal medium spiny neurons (MSNs) are lost. Neuronal replacement therapies aim to replace MSNs through striatal transplantation of donor MSN progenitors, which successfully improve HD-like deficits in rat HD models...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Transplant
Hauptverfasser: Harrison, David J., Roberton, Victoria H., Vinh, Ngoc-Nga, Brooks, Simon P., Dunnett, Stephen B., Rosser, Anne E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2018
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898691/
https://ncbi.nlm.nih.gov/pubmed/29637815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0963689717744788
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