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Fetal haemoglobin induction in sickle cell disease

Fetal haemoglobin (HbF, α2γ2) induction has long been an area of investigation, as it is known to ameliorate the clinical complications of sickle cell disease (SCD). Progress in identifying novel HbF-inducing strategies has been stymied by limited understanding of gamma (γ)–globin regulation. Genome...

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Detalhes bibliográficos
Publicado no:Br J Haematol
Main Authors: Paikari, Alireza, Sheehan, Vivien A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898646/
https://ncbi.nlm.nih.gov/pubmed/29143315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.15021
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