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Sustained analgesic effect of clonidine co-polymer depot in a porcine incisional pain model

BACKGROUND: Previous research suggests that the α(2) adrenergic agonist clonidine, a centrally acting analgesic and antihypertensive, may also have direct effects on peripheral pain generators. However, aqueous injections are limited by rapid systemic absorption leading to off target effects and a b...

詳細記述

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書誌詳細
出版年:J Pain Res
主要な著者: Wilsey, Jared T, Block, Julie H
フォーマット: Artigo
言語:Inglês
出版事項: Dove Medical Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898591/
https://ncbi.nlm.nih.gov/pubmed/29670396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S157018
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