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Bayesian adaptive clinical trials of combination treatments

Randomized clinical trials (RCT) increasingly investigate combination therapies. Strong biological rationale or early clinical evidence commonly suggest that the effect of the combination treatment is importantly greater than the maximum effect of any of the individual treatments. While these relati...

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Detalhes bibliográficos
Publicado no:Contemp Clin Trials Commun
Main Authors: Thorlund, Kristian, Golchi, Shirin, Mills, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898557/
https://ncbi.nlm.nih.gov/pubmed/29696213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2017.11.001
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