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Bayesian adaptive clinical trials of combination treatments

Randomized clinical trials (RCT) increasingly investigate combination therapies. Strong biological rationale or early clinical evidence commonly suggest that the effect of the combination treatment is importantly greater than the maximum effect of any of the individual treatments. While these relati...

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Enregistré dans:
Détails bibliographiques
Publié dans:Contemp Clin Trials Commun
Auteurs principaux: Thorlund, Kristian, Golchi, Shirin, Mills, Edward
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898557/
https://ncbi.nlm.nih.gov/pubmed/29696213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2017.11.001
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