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Favorable outcome of patients with lung adenocarcinoma harboring POLE mutations and expressing high PD-L1

Mutations in polymerase ε (POLE) confer favorable prognosis and outcomes in various cancer types, but their role in non-small cell lung cancer (NSCLC) is unknown. Utilizing the data of 513 patients with adenocarcinoma (LUAD) and 497 patients with squamous cell carcinoma (LUSC) from The Cancer Genome...

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Bibliographic Details
Published in:Mol Cancer
Main Authors: Liu, Liang, Ruiz, Jimmy, O’Neill, Stacey S., Grant, Stefan C., Petty, W. Jeffrey, Yang, Meng, Chen, Kexin, Topaloglu, Umit, Pasche, Boris, Zhang, Wei
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897927/
https://ncbi.nlm.nih.gov/pubmed/29650000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0832-y
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