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ClpC and MecA, components of a proteolytic machine, prevent Spo0A-P-dependent transcription without degradation
In Bacillus subtilis, a proteolytic machine composed of MecA, ClpC and ClpP degrades the transcription factor ComK, controlling its accumulation during growth. MecA also inhibits sporulation and biofilm formation by down-regulating spoIIG and sinI, genes that are dependent for their transcription on...
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| Pubblicato in: | Mol Microbiol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5897911/ https://ncbi.nlm.nih.gov/pubmed/29446505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13928 |
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