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ClpC and MecA, components of a proteolytic machine, prevent Spo0A-P-dependent transcription without degradation

In Bacillus subtilis, a proteolytic machine composed of MecA, ClpC and ClpP degrades the transcription factor ComK, controlling its accumulation during growth. MecA also inhibits sporulation and biofilm formation by down-regulating spoIIG and sinI, genes that are dependent for their transcription on...

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Bibliografske podrobnosti
izdano v:Mol Microbiol
Main Authors: Tanner, Andrew W., Carabetta, Valerie J., Dubnau, David
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897911/
https://ncbi.nlm.nih.gov/pubmed/29446505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13928
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