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Lymphoma exosomes reprogram the bone marrow

In this issue of Blood, Manček-Keber et al report that exosomes and microvesicles (MVs) produced by lymphoma B cells and carrying MyD88(L265P) reprogram the bone marrow environment (BME) by activating endogenous proinflammatory signaling pathways in recipient nonmalignant cells.(1)

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Bibliographic Details
Published in:Blood
Main Author: Whiteside, Theresa L.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897871/
https://ncbi.nlm.nih.gov/pubmed/29650731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-02-830497
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