Resveratrol attenuates high glucose-induced nucleus pulposus cell apoptosis and senescence through activating the ROS-mediated PI3K/Akt pathway

Background: Diabetes mellitus is closely correlated with disc degeneration. Nucleus pulposus (NP) cell apoptosis and senescence are typical cellular features within the degenerative disc. Resveratrol is a newly identified phytoalexin that has protective effects on cartilaginous tissue. Objective: To...

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Bibliographische Detailangaben
Veröffentlicht in:Biosci Rep
Hauptverfasser: Wang, Wenping, Li, Pei, Xu, Jiagang, Wu, Xiangkun, Guo, Zhiliang, Fan, Lijing, Song, Ruipeng, Wang, Jianli, Wei, Li, Teng, Haijun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2018
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897744/
https://ncbi.nlm.nih.gov/pubmed/29273676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20171454
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