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Dileucine-like motifs in the C-terminal tail of connexin32 control its endocytosis and assembly into gap junctions
Defects in assembly of gap junction-forming proteins, called connexins (Cxs), are observed in a variety of cancers. Connexin32 (Cx32; also known as GJB1) is expressed by the polarized cells in epithelia. We discovered two dileucine-based motifs, which govern the intracellular sorting and endocytosis...
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| Veröffentlicht in: | J Cell Sci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5897717/ https://ncbi.nlm.nih.gov/pubmed/29361528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.207340 |
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