Identification, isolation and characterization of human LGR5-positive colon adenoma cells

The intestine is maintained by stem cells located at the base of crypts and distinguished by the expression of LGR5. Genetically engineered mouse models have provided a wealth of information about intestinal stem cells, whereas less is known about human intestinal stem cells owing to difficulty dete...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Dame, Michael K., Attili, Durga, McClintock, Shannon D., Dedhia, Priya H., Ouillette, Peter, Hardt, Olaf, Chin, Alana M., Xue, Xiang, Laliberte, Julie, Katz, Erica L., Newsome, Gina M., Hill, David R., Miller, Alyssa J., Tsai, Yu-Hwai, Agorku, David, Altheim, Christopher H., Bosio, Andreas, Simon, Becky, Samuelson, Linda C., Stoerker, Jay A., Appelman, Henry D., Varani, James, Wicha, Max S., Brenner, Dean E., Shah, Yatrik M., Spence, Jason R., Colacino, Justin A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Stem Cells and Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897593/
https://ncbi.nlm.nih.gov/pubmed/29467240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.153049
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