A mega-analysis of expression quantitative trait loci (eQTL) provides insight into the regulatory architecture of gene expression variation in liver

Genome-wide association studies (GWAS) have identified numerous genetic variants in the human genome associated with diseases and traits. Nevertheless, for most loci the causative variant is still unknown. Expression quantitative trait loci (eQTL) in disease relevant tissues is an excellent approach...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Strunz, Tobias, Grassmann, Felix, Gayán, Javier, Nahkuri, Satu, Souza-Costa, Debora, Maugeais, Cyrille, Fauser, Sascha, Nogoceke, Everson, Weber, Bernhard H. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897392/
https://ncbi.nlm.nih.gov/pubmed/29650998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24219-z
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