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Phosphatase activity tunes two-component system sensor detection threshold

Two-component systems (TCSs) are the largest family of multi-step signal transduction pathways in biology, and a major source of sensors for biotechnology. However, the input concentrations to which biosensors respond are often mismatched with application requirements. Here, we utilize a mathematica...

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Foilsithe in:Nat Commun
Main Authors: Landry, Brian P., Palanki, Rohan, Dyulgyarov, Nikola, Hartsough, Lucas A., Tabor, Jeffrey J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897336/
https://ncbi.nlm.nih.gov/pubmed/29650958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03929-y
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