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CAUSATIVE EFFECTS OF GENETICALLY-DETERMINED HIGH MATERNAL/FETAL ENDOTHELIN-1 ON PREECLAMPSIA-LIKE CONDITIONS IN MICE

Endothelin-1 (ET-1) is implicated in the pathophysiology of preeclampsia (PE). An association between an EDN1 gene polymorphism with high ET-1 and PE was reported in humans, but their cause and effect relationships have not been defined. We examined the pregnancy effects in mice with a modified Edn1...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Li, Feng, Kakoki, Masao, Smid, Marcela, Boggess, Kim, Wilder, Jennifer, Hiller, Sylvia, Bounajim, Carol, Parnell, Scott E., Sulik, Kathleen K., Smithies, Oliver, Maeda-Smithies, Nobuyo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897184/
https://ncbi.nlm.nih.gov/pubmed/29610266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10849
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