Common and divergent features of galactose-1-phosphate and fructose-1-phosphate toxicity in yeast

Toxicity resulting from accumulation of sugar-phosphate molecules is an evolutionarily conserved phenomenon, observed in multiple bacterial and eukaryotic systems, including a number of human diseases. However, the molecular mechanisms involved in sugar-phosphate toxicity remain unclear. Using the m...

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Pubblicato in:Mol Biol Cell
Autori principali: Gibney, Patrick A., Schieler, Ariel, Chen, Jonathan C., Bacha-Hummel, Jessie M., Botstein, Maxim, Volpe, Matthew, Silverman, Sanford J., Xu, Yifan, Bennett, Bryson D., Rabinowitz, Joshua D., Botstein, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2018
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896929/
https://ncbi.nlm.nih.gov/pubmed/29444955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-11-0666
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