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C. elegans MRP-5 Exports Vitamin B12 from Mother to Offspring to Support Embryonic Development

Vitamin B12 functions as a cofactor for methionine synthase to produce the anabolic methyl donor S-adenosylmethionine (SAM) and for methylmalonyl-CoA mutase to catabolize the short-chain fatty acid propionate. In the nematode Caenorhabditis elegans, maternally supplied vitamin B12 is required for th...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Na, Huimin, Ponomarova, Olga, Giese, Gabrielle E., Walhout, Albertha J.M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896776/
https://ncbi.nlm.nih.gov/pubmed/29562169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.100
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