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Trastuzumab Plus Pertuzumab Resistance Does Not Preclude Response to Lapatinib Plus Trastuzumab in HER2‐Amplified Colorectal Cancer

Human epidermal growth factor 2 (HER2) amplification represents a distinct molecular subgroup of colorectal cancers that is associated with anti‐epidermal growth factor receptor resistance and sensitivity to dual HER2 targeting. Although clinical trials have reported activity for trastuzumab/pertuzu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncologist
1. Verfasser: Fakih, Marwan G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: AlphaMed Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896709/
https://ncbi.nlm.nih.gov/pubmed/29330210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0436
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