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Bupivacaine in alginate and chitosan nanoparticles: an in vivo evaluation of efficacy, pharmacokinetics, and local toxicity
OBJECTIVE: This study reports a preclinical evaluation of an alginate/chitosan nanoparticle formulation containing NovaBupi®, a racemic bupivacaine (BVC) containing 25% dextrobupivacaine and 75% levobupivacaine. METHODS: New Zealand White rabbits (n=6) received intraoral or intrathecal injections of...
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| Publicado no: | J Pain Res |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5896646/ https://ncbi.nlm.nih.gov/pubmed/29670395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S158695 |
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