Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas

The breast cancer resistance protein (BCRP/ABCG2) is a maternally-facing efflux transporter that regulates the placental disposition of chemicals. Transcription factors and gene variants are important regulatory factors that influence transporter expression. In this study, we sought to identify the...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Bircsak, Kristin M., Moscovitz, Jamie E., Wen, Xia, Archer, Faith, Yuen, Poi Yu Sofia, Mohammed, Moiz, Memon, Naureen, Weinberger, Barry I., Saba, Laura M., Vetrano, Anna M., Aleksunes, Lauren M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Special Section on Transporters in Drug Disposition and Pharmacokinetic Prediction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896368/
https://ncbi.nlm.nih.gov/pubmed/29386232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.079228
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