Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas

The breast cancer resistance protein (BCRP/ABCG2) is a maternally-facing efflux transporter that regulates the placental disposition of chemicals. Transcription factors and gene variants are important regulatory factors that influence transporter expression. In this study, we sought to identify the...

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Bibliografische gegevens
Gepubliceerd in:Drug Metab Dispos
Hoofdauteurs: Bircsak, Kristin M., Moscovitz, Jamie E., Wen, Xia, Archer, Faith, Yuen, Poi Yu Sofia, Mohammed, Moiz, Memon, Naureen, Weinberger, Barry I., Saba, Laura M., Vetrano, Anna M., Aleksunes, Lauren M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2018
Onderwerpen:
Special Section on Transporters in Drug Disposition and Pharmacokinetic Prediction
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896368/
https://ncbi.nlm.nih.gov/pubmed/29386232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.079228
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