The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A

Autophagy is a critical pathway that degrades intracytoplasmic contents by engulfing them in double-membraned autophagosomes that are conjugated with LC3 family members. These membranes are specified by phosphatidylinositol 3-phosphate (PI3P), which recruits WIPI2, which, in turn, recruits ATG16L1 t...

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Publicat a:Dev Cell
Autors principals: Puri, Claudia, Vicinanza, Mariella, Ashkenazi, Avraham, Gratian, Matthew J., Zhang, Qifeng, Bento, Carla F., Renna, Maurizio, Menzies, Fiona M., Rubinsztein, David C.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896254/
https://ncbi.nlm.nih.gov/pubmed/29634932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.03.008
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