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A Transcriptomic Signature of the Hypothalamic Response to Fasting and BDNF Deficiency in Prader-Willi Syndrome

Transcriptional analysis of brain tissue from people with molecularly defined causes of obesity may highlight disease mechanisms and therapeutic targets. We performed RNA sequencing of hypothalamus from individuals with Prader-Willi syndrome (PWS), a genetic obesity syndrome characterized by severe...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Bochukova, Elena G., Lawler, Katherine, Croizier, Sophie, Keogh, Julia M., Patel, Nisha, Strohbehn, Garth, Lo, Kitty K., Humphrey, Jack, Hokken-Koelega, Anita, Damen, Layla, Donze, Stephany, Bouret, Sebastien G., Plagnol, Vincent, Farooqi, I. Sadaf
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896230/
https://ncbi.nlm.nih.gov/pubmed/29590610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.018
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