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Sex and interleukin-6 are prognostic factors for autoimmune toxicity following treatment with anti-CTLA4 blockade

BACKGROUND: Ipilimumab is a licensed immunotherapy for metastatic melanoma patients and, in the US, as adjuvant treatment for high risk melanoma radically resected. The use of ipilimumab is associated with a typical but unpredictable pattern of side effects. The purpose of this study was to identify...

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Bibliografske podrobnosti
izdano v:J Transl Med
Main Authors: Valpione, Sara, Pasquali, Sandro, Campana, Luca Giovanni, Piccin, Luisa, Mocellin, Simone, Pigozzo, Jacopo, Chiarion-Sileni, Vanna
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896157/
https://ncbi.nlm.nih.gov/pubmed/29642948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1467-x
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