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A Method to Detect Differentially Methylated Loci With Next-Generation Sequencing

Epigenetic changes, especially DNA methylation at CpG loci have important implications in cancer and other complex diseases. With the development of next-generation sequencing (NGS), it is feasible to generate data to interrogate the difference in methylation status for genome-wide loci using case-c...

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Détails bibliographiques
Publié dans:Genet Epidemiol
Auteurs principaux: Xu, Hongyan, Podolsky, Robert H., Ryu, Duchwan, Wang, Xiaoling, Su, Shaoyong, Shi, Huidong, George, Varghese
Format: Artigo
Langue:Inglês
Publié: 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896022/
https://ncbi.nlm.nih.gov/pubmed/23554163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21726
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