Determining Genotypic Drug Resistance by Ion Semiconductor Sequencing With the Ion AmpliSeq™ TB Panel in Multidrug-Resistant Mycobacterium tuberculosis Isolates

BACKGROUND: We examined the feasibility of a full-length gene analysis for the drug resistance-related genes inhA, katG, rpoB, pncA, rpsL, embB, eis, and gyrA using ion semiconductor next-generation sequencing (NGS) and compared the results with those obtained from conventional phenotypic drug susce...

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Detalhes bibliográficos
Publicado no:Ann Lab Med
Main Authors: Park, Joonhong, Shin, So Youn, Kim, Kyungjong, Park, Kuhn, Shin, Soyoung, Ihm, Chunhwa
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society for Laboratory Medicine 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895860/
https://ncbi.nlm.nih.gov/pubmed/29611381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3343/alm.2018.38.4.316
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