Inhibition of cancer stem cell like cells by a synthetic retinoid

Developing novel drugs that can abrogate the growth and metastasis of malignant tumors is a major challenge for cancer researchers. Here we describe a novel synthetic retinoid, namely WYC-209, which inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs), known to resist...

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Udgivet i:Nat Commun
Main Authors: Chen, Junwei, Cao, Xin, An, Quanlin, Zhang, Yao, Li, Ke, Yao, Wenting, Shi, Fuchun, Pan, Yanfang, Jia, Qiong, Zhou, Wenwen, Yang, Fang, Wei, Fuxiang, Wang, Ning, Yu, Biao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895803/
https://ncbi.nlm.nih.gov/pubmed/29643385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03877-7
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