Pro-inflammatory cytokines activate hypoxia-inducible factor 3α via epigenetic changes in mesenchymal stromal/stem cells

Human mesenchymal stromal/stem cells (hMSCs) emerged as a promising therapeutic tool for ischemic disorders, due to their ability to regenerate damaged tissues, promote angiogenesis and reduce inflammation, leading to encouraging, but still limited results. The outcomes in clinical trials exploring...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cuomo, Francesca, Coppola, Antonietta, Botti, Chiara, Maione, Ciro, Forte, Amalia, Scisciola, Lucia, Liguori, Giuseppina, Caiafa, Ilaria, Ursini, Matilde Valeria, Galderisi, Umberto, Cipollaro, Marilena, Altucci, Lucia, Cobellis, Gilda
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895792/
https://ncbi.nlm.nih.gov/pubmed/29643458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24221-5
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