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Neurofibromin knockdown in glioma cell lines is associated with changes in cytokine and chemokine secretion in vitro
The neurofibromin-1 tumor suppressor gene (NF1) is altered in approximately 20% of sporadic glioblastoma (GBM) cases. NF1 deficient GBM frequently shows a mesenchymal gene expression signature, suggesting a relationship between NF1 status and the tumor microenvironment. To identify changes in the pr...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5895785/ https://ncbi.nlm.nih.gov/pubmed/29643433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24046-2 |
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